Rhinovirus - MegaMicro

Search
Go to content

Main menu:

Rhinovirus

Microbiology > Virology > RNA viruses > Single Stranded RNA viruses > Picornavirus
 

 
  1. Structure
  2.  
    1. Part of the Picornavirus family
    2.   
      1. Small virus (20-30 nm)
        
    3. Naked ssRNA+, icosahedral capsid
     
  3. Pathobiology
  4.  
    1. Transmitted by respiratory droplets
    2.   
    3. Enters cell by attaching ICAM-1
    4.   
      1. Present on many cells such as epithelial, fibroblast, B-lymphoblast cells
        
    5. Acid labile
    6.   
      1. All other viruses in the picornavirus family are acid stabile
        
    7. Grows best at 33-35˚C
    8.   
      1. Infects the upper respiratory tract because it is cooler than body temperature
      2.    
      3. Able to survive outside the human body for up to 3 hours
        
    9. Multiple serotypes (>100)
    10.   
      1. Previous infection does not provide immunity from subsequent infections
      2.    
      3. Hard to develop a vaccine
     
  5. Epidemiology
  6.  
    1. Transmitted through direct contact, fomites, and respiratory droplets
    2.   
    3. Typically see cases in the Autumn or winter
     
  7. Lab Diagnosis
  8.  
  9. Disease Manifestations
  10.  
    1. Common Cold
    2.   
    3. Non-specific URI,       rhinorrhea, and nasal obstruction
    4.   
    5. Therapy: supportive care
     
  11. Prevention: washing hands
  12.  
  13. Differential diagnosis: Other causes of the common cold
  14.  
    1. Rhinovirus
    2.   
    3. Coronavirus
    4.   
    5. Adenovirus
    6.   
    7. Influenza C virus
    8.   
    9. Coxsackie virus
Related concepts
common cold
 
Copyright 2016. All rights reserved.
Back to content | Back to main menu